There are other genetic mutations that are associated with an increased breast cancer risk, but are much less widespread than BRCA1 and BRCA2, are p53 and PTEN, each associated with less than 1% of cases.

The benign breast lesions such as papillomas, commonly referred fibradenomas and fibrocystic changes are not premalignant and not associated with an increased risk of breast cancer. However, abnormalities such as hyperplasia heatwave proliferating, atypical loboluliar associated with a significantly higher relative risk.

IONIZING RADIATION

Exposure to low dose radiation is clearly carcinogenic, with increased breast cancer as the exposure dose. This risk also depends on age, so that women exposed during adolescence are those with the highest risk, while those exposed after age 50 virtually no added risk. The latency period from exposure to the breast cancer diagnosis is 10 or 15 years older

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Since 1990, the mortality rate from breast cancer has declined in the United States by 24% and similar reductions have been observed in other countries. Mathematical models suggest that both the use of mammography and the availability of adjuvant chemotherapy and tamoxifen as well as contributing to this improvement. Although breast cancer has traditionally been less common in non-industrialized countries, its incidence in these areas is increasing.

In our country according to recent data from the National Registry of Tumors, ranks second in incidence and remember that in the course of a lifetime, one in eight women will be diagnosed with breast cancer.

It is believed that 50% of women diagnosed with breast cancer has identifiable risk factors other than age and gender. Certain hormonal and reproductive factors and lifestyle, diet and environment are related to the risk. In addition to personal or family history of this neoplasm, histories of benign breast disease is another predisposing factor.

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