postheadericon The Benign Breast And Ionizing Radiation

breast cancerMany studies show that the risk of a woman suffering from breast cancer increases with the number of affected relatives. Between 10% and 20% of women with breast cancer have a relative in the first or second degree affected by this cancer and 50% claim to have at least one parent at any grade. Approximately 5% of women with breast cancer have a family history that points to the mutation of a gene confers a predisposition to high risk, have isolated two of these genes, BRCA1 and BRCA2, but these genes only account for between 30 and 40% of familial breast cancers that appear as an automatic dominant, so do not justify the etiology in a significant number of high-risk families.

There are other genetic mutations that are associated with an increased breast cancer risk, but are much less widespread than BRCA1 and BRCA2, are p53 and PTEN, each associated with less than 1% of cases.

The benign breast lesions such as papillomas, commonly referred fibradenomas and fibrocystic changes are not premalignant and not associated with an increased risk of breast cancer. However, abnormalities such as hyperplasia heatwave proliferating, atypical loboluliar associated with a significantly higher relative risk.

IONIZING RADIATION

Exposure to low dose radiation is clearly carcinogenic, with increased breast cancer as the exposure dose. This risk also depends on age, so that women exposed during adolescence are those with the highest risk, while those exposed after age 50 virtually no added risk. The latency period from exposure to the breast cancer diagnosis is 10 or 15 years older

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